Collaborative Research Resources (Laboratory of Cell and Tissue Biology)
Anatomy, Bone cell biology
Elucidating the development and homeostasis of the skeleton through cell-cell interaction.
Thesis Advisor:Master's
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Doctoral
Electron Microscope Laboratory
Biochemistry・Neuroscience・Microbe-Host Interaction・Chiral Biology
We investigate how the structural asymmetry of biomolecules influences metabolism, physiological functions, and disease processes at the cellular and organismal levels, and explore its implications for biological evolution and symbiosis.
Medical Education Center
Medical education; Nephrology
Medical pedagogy including the development of education utilizing ICT (Information and Computer Technology), and development of the interprofessional education program. Elucidating mechanisms of water, electrolyte, and acid-base disorders; renal tubule differentiation and regeneration.
Medical Education Center
Family medicine, healthcare professional education, inter/trans professional education
We conduct research that clarifies the complexity and comprehensive perspectives that family medicine covers, as well as research of healthcare professional education and/or inter/trans professional education that is not limited to physicians involved in medicine, and also deals with quantitative/qualitative data.
Thesis Advisor:Master's
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Doctoral
Medical Education Center
Medical Education: Exploring Effective Training for Healthcare Professionals and Interprofessional Collaboration.Endocrinology and Metabolism: Investigating the Mechanisms Underlying Metabolic Disorders Caused by Aging and Obesity, and Developing Novel Preventative Strategies for them.
Center for Preventive Medicine
Clinical Oncology, Preventive Medicine, Gastroenterology
Developing new treatments and diagnostic methods of cancer by elucidating molecular pathogenesis.
Center for Preventive Medicine
Preventive Medicine, Gastroenterology, Gastrointestinal Endoscopy
Elucidation of pathophysiology of gastrointestinal diseases, especially small intestinal diseases.Development of diagnostic methods using gastrointestinal endoscopy, especially capsule endoscopy.
Apheresis and Dialysis Center
Chronic Kidney Disease and Cardiovascular Complications
Understanding the molecular mechanisms of the development of chronic kidney disease, focusing on chronic inflammation. Elucidation of the mechanisms of cardiovascular complications in chronic kidney disease.
Center for Diagnostic and Therapeutic Endoscopy
Diagnosis & therapeutics for gastrointestinal neoplasmsResearch & development for minimally invasive treatment using endoscopy
Research & development of endoscopic resection methods and medical devices for superficial gastrointestinal tumors, especially for duodenal tumors, which are extremely difficult to treat.
Thesis Advisor:Master's
、
Doctoral
Cancer Center (Advanced Minimally Invasive Therapy Unit)
Minimally Invasive treatment for Gastrointestinal Neoplasia
Developing new procedures for advanced minimally-invasive treatments such as endoscopic resection and laparoscopic resection. And developing new therapeutic instruments for advanced minimally-invasive treatments, including NOTES (natural orifice translumenal endoscopic surgery) and LECS (laparoscopy and endoscopy combined surgery).
Thesis Advisor:Master's
、
Doctoral
Center for Transfusion Medicine and Cell Therapy
Transfusion Medicine, Hematopoietic Stem Cell Transplantation, Hematology, Cell Therapy and Regenerative Medicine
Our research focuses on the development of management systems for blood components, cellular products, and regenerative medicine products. We also investigate how to optimize stem cell collection procedures, characterize the biological features of mobilized stem cells, and understand complications that arise after allogeneic transplantation or CAR-T cell therapy. In addition, we aim to identify factors that influence the safety, efficiency, and quality of cell therapy in real-world clinical settings.
Thesis Advisor:Master's
、
Doctoral
Institute for Integrated Sports Medicine
Sport Related Injuries and Disorders in Upper Extremity, Hand and Elbow Surgery, General Orthopaedic Surgery,
1)Biomechanics:Biomechanics of the elbow in the throwingathlete; 2)Effects of adipose-derived mesenchymal stem/stromal cell line on enthesopathy; 3)Peripheral Nerve:Peripheral nerve regeneration with stem cells purified from neural crest-like cells, derived from human induced pluripotent stem cells
Thesis Advisor:Master's
、
Doctoral
Center for Medical Genetics
Clinical Genetics, Teratology, Pediatrics
1) Clinical genomics inclulding diagnosis and management of rare diaseases and genetic counseling. 2) Elucidation of genetic causes of genetic diseases with a focus on "undiagnosed diseases".
Thesis Advisor:Master's
、
Doctoral
Center for Medical Genetics
Medical bioinformatics
Our research focuses on hereditary diseases, particularly rare and intractable disorders, aiming to develop methods for the identification of causative variants through advanced bioinformatics approaches. We also conduct association studies between genetic variants and a wide range of phenotypes, including various quantitative traits.
Human Biology-Microbiome-Quantum Research Center (Bio2Q)
Neuroscience
Our research focuses on the mechanisms of synapse formation, maintenance, and remodeling in the central, peripheral, autonomic, and enteric nervous systems. We aim to elucidate the functions of neural circuits and inter-organ communication, and to develop novel therapies for disorders resulting from their dysfunction.
Thesis Advisor:Master's
、
Doctoral
Human Biology-Microbiome-Quantum Research Center (Bio2Q)
Microbiome. Computational Biology Research Content
I lead the computational microbiome research group, and we are interested in understanding the role the microbiome plays in health and disease using large datasets, computational methods, and artificial intelligence approaches. We analyze metagenomics and metabolomics data to decipher the functions, role and evolution of bacteria living with us humans.
Thesis Advisor:Master's
、
Doctoral
Human Biology-Microbiome-Quantum Research Center (Bio2Q)
Primate proteostasis, Cell repair after protein damage, Protein disaggregation, Neurodegeneration
Cellular proteostasis regulating protein folding, trafficking, and degradation helps maintain cell survival. Its disruption causes toxic protein aggregation, worsening with aging and driving protein conformational diseases. We pioneer in investigating primate-specific proteostasis adaptations, enhancing protein disaggregation and cell repair along the gut-brain axis with a focus on dysbiosis and neurodegeneration.
Thesis Advisor:Master's
、
Doctoral
English
Early Modern English Literature
The literary and physiological aspects of two apparently conflicting phenomena in early modern English literature: the significance attached to the soothing effects of laughter, and the cult of melancholy.
English
Medical English education, Task-based Language Teaching (TBLT)
My research focuses on Medical English education, with a particular focus on the application of CLIL and task-based methodologies in collaborative teaching involving clinicians and language teachers. I am also engaged in analysis of English questions in the Japanese National Medical Licensing Exam.
Thesis Advisor:Master's
、
Doctoral
German
Austria Literature between the World Wars,Modern Austrian Literature,German as a foreign language
Text-immanent interpretation of Austrian literature in the interwar period as well as an examination of the characteristics of Austrian literature through the method concerning the sociology of literature. Interpretation and synchronic and diachronic study of Modern Austrian literature in the postwar era. Study of German vocabulary required for each level.
Physics
Optical Measurements of Soft Matter
Thermal agitation of the interior and surface of matter. Through these measurements, we can gain knowledge not only concerning thermal fluctuation, but moisture and elasticity can also be measured without physical contact. Pursuing clinical applications through performing measurements of various materials.
Thesis Advisor:Master's
Physics
Quantum computation of nonequilibrium dynamics of quantum field theories
Applications of quantum computers to solve nonequilibirum dynamics of quantum many-body systems.In particular, nonequilibrium dynamics of lattice gauge theories are studied to understand Our universe.
Biology
Immnology, Microbioligy
The goal is to establish phage therapy specific for pathogenic bacteria.In addition to the isolation of natural phage, we are also looking into the creation of phage that are effective against phage-resistant bacteria.We are working to establish new treatment strategies for antimicrobial-resistant (AMR).
Thesis Advisor:Master's
、
Doctoral
Biology
Comparative Zoology, Tardigrade Biology
Research concerning the natural history surrounding tardigrades, such as life history traits of terrestrial tardigrades which possess high resistance to desiccation, taxonomy of marine tardigrades, micromorphology of gametogenesis, etc.