Faculty

General and Gastroenterological Surgery

Gastroenterological surgery (esophagus and stomach); surgical oncology; endoscopic treatment, endoscopic surgery; solid tumor multidisciplinary therapies; surgical infections, bodily reactions to invasive surgery; individually minimized minor surgery using sentinel lymph node theory

Research utilizing an approach based on the sentinel node theory. Analyzing the mechanisms of metastasis of lymph node cancers and their regulation. Minimally invasive treatment for early upper GI cancer. Multidisciplinary treatment method for advanced upper GI cancer Research into reactions to invasive surgery, and surgery-related infections.

General and Gastroenterological Surgery

Gastroenterological Surgery, Hepatobiliary and pancreatic surgery, Transplant Surgery, Surgical Oncology, Endoscopic surgery, Solid tumor multidisciplinary therapy, Endoscopic diagnosis & Treatment

Developing surgical methods with a basis of major surgery and minimally invasive treatments for Hepatobiliary and pancreatic disease. The clinical research to improve the treatment outcomes for pancreatic cancer. Translational research to aim the clinical application such as biomarkers from molecular abnormality analysis related to the pathogenesis of pancreatic cancer.

Pediatric Surgery

Cellular kinetics of pediatric cancer; pediatric cancer stem cells, fetal surgery

Basic research on cellular kinetics and cancer stem cells of pediatric cancers associated with clinical trials of new treatment strategies. Develoment of fetal diagnostic and surgical techniques.

Cardiovascular Surgery

Cardiovascular surgery; Endovascular stent-graft; minimally invasive cardiac surgery; organ protection methods; artificial heart and blood vessels

Developing surgical methods with a basis in implementing major surgery and minimally invasive treatments for cardiac and aortic diseases; and research on perioperative organ protection methods. Development of new treatments and diagnostic methods for aortic aneurysm and aortic dissection.

General Thoracic Surgery

General thoracic surgery; thoracic oncology; TNM stage classification of cancer (UICC); cancer registry and database development; minimally invasive thoracic surgery

Multidisciplinary therapy of lung cancer, thymic epithelial tumor, pleural mesothelioma, and other thoracic malignancies; clinical trials including surgery for thoracic malignancies; TNM stage classification (UICC); development of minimally-invasive surgical techniques for lung cancers; lung cancer registry.

General Thoracic Surgery

General thoracic surgery, Thoracic oncology, Multimodality treatment, Minimally invasive thoracic surgery

Surgical treatment for lung cancer, thymic epithelial tumor, malignant pleural mesothelioma, and other thoracic malignancies; clinical trials including surgery for thoracic malignancies; development of multimodality treatment and minimally invasive surgery for thoracic malignancies.

Neurosurgery

Brain tumors; pituitary tumors; endoscopic skull base surgery; immunotherapy

Development of minimally invasive treatments for brain tumors, pituitary tumors, and skull base tumors (endonasal endoscope surgery, 3D surgical simulation). Development of new treatments for malignant brain tumors (immunotherapy, gene therapy, and cell therapy).

Orthopedic Surgery

Spine Surgery, Minimally Invasive Spine Therapies, Scoliosis

Developing prosthetics necessary for spinal surgery. Identifying scoliosis susceptible genes and developing new assesment and surgical methods. Multicenter collaborative research on spine disorders. Researching spine aging through MRI machines. Researching the invasiveness of spine surgery.

Orthopedic Surgery

Spine and Spinal Cord Surgery, Spinal Cord Disorder Therapies, Neuroscience (Spinal Cord Regeneration, Growth factors, Neuroimaging)

Multicenter collaborative research on spine and spinal cord disorders. Developing regenerative medicine for musculoskeletal disorders, especially for spinal cord injury and new assessment methods through MRI and CT. Working on (1) iPS cell-based transplant therapies, (2) hepatocyte growth factors, (3) suppression of axonal growth inhibitors.

Institute for Integrated Sports Medicine

Sport Related Injuries and Disorders in Upper Extremity, Hand and Elbow Surgery, General Orthopaedic Surgery,

1)Biomechanics：Biomechanics of the elbow in the throwingathlete; 2)Effects of adipose-derived mesenchymal stem/stromal cell line on enthesopathy; 3)Peripheral Nerve：Peripheral nerve regeneration with stem cells purified from neural crest-like cells, derived from human induced pluripotent stem cells

Orthopedic Surgery

General knee surgery, Rheumatoid arthritis, Sports medicine

Elucidating the mechanism of joint destruction in osteoarthritis, rheumatoid arthritis, and biomaterial-related arthritis. Currently focusing on anatomically aligned total knee arthroplasty and regenerative medicine for cartilage degeneration in knee osteoarthritis.

Orthopedic Surgery

Orthopedic surgery, Spine surgery

Establishment of the novel treatments for spinal scoliosis, including conservative and surgical treatments. Research for exploring the pathology of spinal scoliosis including involvement of environmental and genetic factors. Establishment of novel treatments for lumbar spinal canal stenosis based on the pathology of the disease.

Rehabilitation Medicine

Cancer Rehabilitation Medicine, Angiology, Clinical Neurophysiology, Exercise Physiology

1) Developing cancer rehabilitation programs; 2) Developing a cancer functional assessment set; 3) Development of rehabilitation program for cancer patients in the outpatient setting; 4) Developing therapeutic exercises for cancer cachexia; 5) Developing evaluation methods and therapeutic exercises for lymphedema using fluorescent lymph angiography

Rehabilitation Medicine

Neurorehabilitation

I work with patients of all ages to recover from the sequelae in brain diseases. I develop and clinically apply neurorehabilitation methods based on brain science and neurophysiology.

Plastic and Reconstructive Surgery

Skin Regeneration (Including Skin Appendages)

Developing skin reproduction methods that utilize adult animal cells based on the phenomenon of skin regeneration in fetal mice, and analyzing its cellular and molecular mechanisms.

Plastic and Reconstructive Surgery

Plastic and reconstructive surgery(micro surgery), Facial nerve palsy, Pediatric plastic surgery

Platelets, which contain many growth factors have wound healing effects in addition to hemostatic and coagulation effects. Regenerative medicine technology enables the stable production of platelets in large quantities, and is developing new wound healing agents by concentrating platelets.

Pediatrics

Developmental Neurobiology, the Cell Cycle, Neural Stem Cells, Cerebral Cortex Assembly

Research concerning mechanisms of developmental disorders of higher cortical function with a focus on proliferation/differentiation behavior of neural stem cells/progenitors in normal and abnormal histogenesis of the neocortex.

Pediatrics

Pediatric Cardiology, Clinical Cardiac Development

Congenital heart disease (CHD) occurs in nearly 1% of all live births and is the major cause of infant mortality and morbidity. Our research for identifying genetic causes and molecular mechanisms of CHD is essential not only to fully understand the disease, but also to enhance current knowledge about new preventive and/or therapeutic strategies.

Pediatrics

Pediatric endocrinology (disorders of sex development, adrenocortical disorders, hypogonadism, precocious puberty, hypopituitarism, bone dysplasia)

Clinical and basic researches in disorders of sex development (DSD) or adrenocortical disorders for investigating the mechanism underlying sex differentiation or adrenal development and the etiology, pathophysiology, and novel treatment of DSD or adrenocortical disorders.

Pediatrics

Pediatrics, Neonatology, Pediatric Nephrology

Research in development of kidney function and morphogenesis, especially focusing on epigenetic modification in kidneys of preterm and low birth weight babies.

Gynecology

Gynecologic Oncology, Gynecologic Pathology, Molecular Cytogenetics, Hereditary Cancer, Fertility-Preserving Therapy in Gynecological Cancer, Cancer Screening

Pursuing new prevention and therapeutic methods based on analysis of cancer genomes and molecular cytogenesis; and also investigating diagnostic performance of profiles of biomarkers in cancer cells.

Gynecology

Endometrial cancer, Familial tumor, Uterine transplantation

Genetics and epigenetics of tumorigenesis in gynecologic cancer, with a particular focus on hereditary cancer, and uterine transplantation as a new technique in oncofertility.

Obstetrics

Perinatal Medicine, Reproductive Medicine, Clinical Genetics, Embryology

Molecular biology concerning mammalian development; fetal medicine ranging from diagnostics to therapies; research and development of treatments of perinatal diseases utilizing mesenchyme stem cells.

Obstetrics

Reproductive Medicine, Reproductive Endocrinology, Stem Cell Medicine, Regenerative Medicine, Clinical Genetics

Developing new reproductive regenerative medicine aiming for the restoration and rehabilitation of reproductive capabilities, and to understand the clinical condition mechanisms of reproductive and perinatal disorders from the perspetive of stem cells as well as the endocrine system and molecular genetics.

Ophthalmology

Understanding Eyeball Optical System Conditions, Analyzing Visual Performance

Research related to visual optics and function. On the basis of the results of basic optical analysis using PC simulation, optical bench testing, and clinical data, we are trying to improve quality of vision, and aim to construct the ideal optical system for the human eye in daily activities.