123 Results

All Departments

Name/Position

Department/Specialty/Research Content

Thesis Advisor

  • Sadakazu Aiso
    Professor

    Anatomy


    Morphogenetic mechanisms of tissue and cells



    Molecular and genetic elucidation as well as morphological study of the process by which tissue and cells are formed through cell differentiation, especially focusing on the function of D-amino acids.

    Thesis Advisor:Master's
    Doctoral

  • Kazunori Nakajima
    Professor

    Anatomy


    Mechanisms of cerebral cortical development



    We are interested in the cellular and molecular mechanisms of how the cells in the central nervous system, in particular the cells in the cerebral cortex, are born, migrate to their final destinations, develop unique structures such as layers, and finally form such a complex network to enable the various higher brain functions. We are also investigating how these developmental processes are disturbed by various perturbations.

    Thesis Advisor:Master's
    Doctoral

  • Nobuaki Imanishi
    Associate Professor

    Anatomy


    Three dimensional vascular anatomy of human body



    Clarification of three dimensional structure of arteries and veins by investigating radiographically various organs of fresh cadavers injected systemically with radiopaque. The objective of the research is development of new surgical methods based on the three dimensional anatomy.

  • Hideyuki Okano
    Professor

    Physiology


    CNS development and regeneration



    Elucidating the clinical states of neurological disorders, and research into regenerative medicine of the CNS using neural stem cells and iPS cell technology. Development of genetically modified primate techniques, creation of new models of neurological and mental disorders, and the elucidation of the mechanisms of brain development and higher level brain function.

    Thesis Advisor:Master's
    Doctoral

  • Michisuke Yuzaki
    Professor

    Physiology


    Synapse formation and plasticity as the basis of higher brain functions and neuropsychiatric disorders



    Synapses are not only formed during development, but also continuously modified according to neuronal activities throughout adulthood. Synaptic plasticity is believed to be the basis of all higher brain functions, including learning and memory. Moreover, recent genetic studies have revealed that many neuropsychiatric disorders are caused by defects in genes encoding synaptic molecules. Thus, we aim to understand mechanisms by which synapses are formed, maintained and eliminated by neuronal activities using electrophysiological, molecular biological, and behavioral approaches.

    Thesis Advisor:Master's
    Doctoral

  • Wataru Kakegawa
    Associate Professor

    Physiology


    Synaptology toward an understanding of molecular mechanisms for learning and memory



    Synapses, which connect neurons in the brain, dynamically change throughout life. We address the issues how synapses are formed and function, and how synaptic events affect behaviors, thereby uncovering the molecular mechanisms of learning and memory.

  • Takuya Shimazaki
    Associate Professor

    Physiology


    Neural stem cell biology



    Elucidating the mechanisms of spatio-temporal regulation of the self-renewal and differentiation potential of neural stem cells which provide the basis for the central nervous system histogenesis.

  • Jun Kohyama
    Associate Professor

    Physiology


    Specialization trait acquisition mechanism of nervous system/neural cells



    Clarification of the maintenance and acquisition mechanisms of CNS cell group differentiation from an epigenetic expression regulation mechanism perspective; development of cell lineage regulation techniques.

  • Masato Yasui
    Professor

    Pharmacology


    Water Biology and Medicine: understanding of in vivo water dynamics and the roles of aquaporins



    A double-sided analysis of the structure-function relationship of aquaporins (water channels) consisting of a biochemical approach and molecular dynamic simulations. Furthermore, researching aquaporin regulation mechanisms and high-order functions, and building a basis for drug development.

    Thesis Advisor:Master's
    Doctoral

  • Yoshiro Sohma
    Associate Professor

    Pharmacology


    Channel transporter molecular pharmacology (membrane transport protein)



    Developing systematic control techniques of ABC transporters through examining the mechanism of action of ATP dependent pump engines common to physiologically important ABC transporter superfamilies.

  • Makoto Suematsu
    Visiting Professor

    Biochemistry


    Biochemistry of diseases, Gas biology



    Investigating molecular mechanisms for genetic regulation of metabolism and metabolic regulation of genetics using advanced mass spectrometry

    Thesis Advisor:Master's
    Doctoral

  • Haruhiko Shiomi
    Professor

    Molecular Biology


    RNA biology



    Understanding molecular mechanisms underlying genomic quality control in light of stem cell formation and maintenance through characterizations of molecular pathways leading to transposon silencing including RNAi. In addition, understanding diseases caused by defects in RNAi and its related pathways.

    Thesis Advisor:Master's
    Doctoral

  • Kuniaki Saito
    Associate Professor

    Molecular Biology


    Epigenetics



    Clarifying the epigenetic molecular basis and the functional role of small RNAs in transposable element regulation through biochemical techniques. Furthermore, examining the mechanisms and causes of diseases related to the failure of transposable element regulation, and investigating new molecular targets for diseases.

  • Kazuyuki Omae
    Professor

    Preventive Medicine and Public Health


    Occupational and environmental epidemiology and toxicology



    Health risk assessment of occupational and environmental toxic chemicals by using optimal research methods (epidemiology, experiments on laboratory animals), and the application of the research outcomes to the control of health problems.

    Thesis Advisor:Master's
    Doctoral

  • Toru Takebayashi
    Professor

    Preventive Medicine and Public Health


    Preventive medicine; environmental and occupational medicine



    To achieve primary prevention for all in every community, my main research topic is tailor-made preventive medicine based on epidemiology with population-based cohort studies, combining multi-omics technologies, metabolomics in particular. Furthermore, pursuing social prevention efforts through establishing environmental and occupational standards for protecting population and workers' health through a scientific risk assessment process.

    Thesis Advisor:Master's
    Doctoral

  • Tomonori Okamura
    Professor

    Preventive Medicine and Public Health


    Public health; lifestyle-related disease; epidemiology; nutrition; community medicine; international collaborative research



    We are seeking to identify new biomarkers that predict incidence of lifestyle-related diseases, and also developing novel lifestyle modification (diet, etc.) that will prevent various diseases through large-scale cohort studies and international collaborative studies. Also we are performing regional intervention research through health training and community education, health policy making studies (Health Japan 21, Data Health), and establishing clinical guidelines based on epidemiologic evidence.

    Thesis Advisor:Master's
    Doctoral

  • Satoshi Iwata
    Professor

    Infectious Diseases


    Bacterial infectious diseases; pediatric infectious diseases; anti-microbial agents; infection control; immunizations/vaccinations; intestinal flora



    Aiming for the improvement of the diagnosis, treatment, and prevention of infectious diseases through epidemiological analysis and clinical pharmacological analysis of various infectious diseases such as respiratory tract infections ; urinary tract infections; central nervous system infections; bacteremia; medical device- related infections; drug-resistant bacterial infections and parasitic infections; and also through the spread of vaccination.

    Thesis Advisor:Master's
    Doctoral

  • Michiie Sakamoto
    Professor

    Pathology


    Tumor pathology, Liver pathology, Molecular pathology, Pathology informatics



    Analyze molecular mechanisms of human cancer development and progression. Establish precisional pathologic diagnosis, quantitative pathologic diagnosis and information technology based pathology.

    Thesis Advisor:Master's
    Doctoral

  • Yae Kanai
    Professor

    Pathology


    Pathology; Cancer epigenetics; Integrative disease omics analysis



    To participate in genome medicine and preventive/pre-emptive medicine by understanding the molecular mechanisms of diseases, therapeutic and diagnostic targets are explored based on integrative disease omics analysis, especially epigenome analysis, in human cancers derived from various organs, histopathologically-recognized precancerous lesions and cancer-prone metabolic and/or inflammatory disorders.

    Thesis Advisor:Master's
    Doctoral

  • Hajime Okita
    Associate Professor

    Pathology


    Pathology



    Analysis of molecular genetic abnormalities of cancer, particularly in pediatric tumors and sarcomas in order to ascertain their development and progression mechanisms, with the goal of developing molecular diagnosis and treatment methods.

  • Shigeo Koyasu
    Visiting Professor

    Microbiology and Immunology


    Immunology; cell biology



    Analyzing the regulation mechanisms of natural and acquired immunity using molecular cell biological techniques and mouse models. Recently focusing on innate lymphoid cells.

    Thesis Advisor:Master's
    Doctoral

  • Akihiko Yoshimura
    Professor

    Microbiology and Immunology


    Molecular immunology; understanding disease centered around cytokines and infllammation



    1. Analysis of immune regulation mechanims by CIS/SOCS family genes and cytokines.2. Analysis of cytokines and their signl transduction in various inflammatory diseases.3. Functional analysis of Spred/Sprouty protein family.4. T-cell reprogramming.

    Thesis Advisor:Master's
    Doctoral

  • Kenya Honda
    Professor

    Microbiology and Immunology


    Immunology; microbiology; intestinal microbiota



    Clarifying effects of the intestinal microbiota on the host physiology. Also investigating the mechanisms of host response to pathogens.

    Thesis Advisor:Master's
    Doctoral

  • Masaki Q. Fujita
    Professor

    Legal Medicine


    Forensic pathology; sudden death study



    Investigating the pathogenesis and predisposition of sudden unexpected death syndrome in young Asian males by performing genetic and comparative epidemiological studies. Establishing objective diagnosis methods in forensic medicine.

    Thesis Advisor:Master's
    Doctoral

  • Hiroaki Miyata
    Professor

    Health Policy and Management


    Health policy and management; Quality of healthcare; Epidemiology; Evaluation; Social science method



    Health policy research and clinical research for i. Quality improvement initiative, ii. Healthcare technology/diagnosis/treatment innovation , iii. Sustainable, optimal healthcare system.

    Thesis Advisor:Master's
    Doctoral