Faculty

General Thoracic Surgery

General thoracic surgery, Thoracic oncology, Multimodality treatment, Minimally invasive thoracic surgery

Surgical treatment for lung cancer, thymic epithelial tumor, malignant pleural mesothelioma, and other thoracic malignancies; clinical trials including surgery for thoracic malignancies; development of multimodality treatment and minimally invasive surgery for thoracic malignancies.

Neurosurgery

Brain tumors; pituitary tumors; endoscopic skull base surgery; immunotherapy

Development of minimally invasive treatments for brain tumors, pituitary tumors, and skull base tumors (endonasal endoscope surgery, 3D surgical simulation). Development of new treatments for malignant brain tumors (immunotherapy, gene therapy, and cell therapy).

Neurosurgery

Clinical and experimental research on cerebrovascular disorders and brain tumor

・Research on cerebrovascular disorders including AV shunt diseases　・Development of novel and innovative endovascular treatment and devices　・Research on genetic AV shunt disease including hereditary hemorrhagic・telangiectasia

Orthopedic Surgery

Spine Surgery, Minimally Invasive Spine Therapies, Scoliosis

Developing prosthetics necessary for spinal surgery. Identifying scoliosis susceptible genes and developing new assesment and surgical methods. Multicenter collaborative research on spine disorders. Researching spine aging through MRI machines. Researching the invasiveness of spine surgery.

Orthopedic Surgery

Spine and Spinal Cord Surgery, Spinal Cord Disorder Therapies, Neuroscience (Spinal Cord Regeneration, Growth factors, Neuroimaging)

Multicenter collaborative research on spine and spinal cord disorders. Developing regenerative medicine for musculoskeletal disorders, especially for spinal cord injury and new assessment methods through MRI and CT. Working on (1) iPS cell-based transplant therapies, (2) hepatocyte growth factors, (3) suppression of axonal growth inhibitors.

Orthopedic Surgery

Orthopedic surgery, Spine surgery

Establishment of the novel treatments for spinal scoliosis, including conservative and surgical treatments. Research for exploring the pathology of spinal scoliosis including involvement of environmental and genetic factors. Establishment of novel treatments for lumbar spinal canal stenosis based on the pathology of the disease.

Orthopedic Surgery

hand and elbow surgery,joint surgery for rheumatoid arthritis

I am conducting research on the establishment of safe and reliable surgical techniques for hand and elbow disorders caused by rheumatoid arthritis and osteoarthritis. Additionally, I am also working on the development of novel artificial nerves for peripheral nerve injuries.

Rehabilitation Medicine

Cancer Rehabilitation Medicine, Angiology, Clinical Neurophysiology, Exercise Physiology

1) Developing cancer rehabilitation programs; 2) Developing a cancer functional assessment set; 3) Development of rehabilitation program for cancer patients in the outpatient setting; 4) Developing therapeutic exercises for cancer cachexia; 5) Developing evaluation methods and therapeutic exercises for lymphedema using fluorescent lymph angiography

Rehabilitation Medicine

Neurorehabilitation

I work with patients of all ages to recover from the sequelae in brain diseases. I develop and clinically apply neurorehabilitation methods based on brain science and neurophysiology.

Plastic and Reconstructive Surgery

Skin Regeneration (Including Skin Appendages)

Developing skin reproduction methods that utilize adult animal cells based on the phenomenon of skin regeneration in fetal mice, and analyzing its cellular and molecular mechanisms.

Plastic and Reconstructive Surgery

Plastic and reconstructive surgery(micro surgery), Facial nerve palsy, Pediatric plastic surgery

Platelets, which contain many growth factors have wound healing effects in addition to hemostatic and coagulation effects. Regenerative medicine technology enables the stable production of platelets in large quantities, and is developing new wound healing agents by concentrating platelets.

Pediatrics

Pediatric endocrinology, molecular genetics

Performing comprehensive genetic analysis of congenital endocrine disorders and pathophysiological investigations using cellular and animal models.

Pediatrics

Pediatric endocrinology (disorders of sex development, adrenocortical disorders, hypogonadism, precocious puberty, hypopituitarism, bone dysplasia)

Clinical and basic researches in disorders of sex development (DSD) or adrenocortical disorders for investigating the mechanism underlying sex differentiation or adrenal development and the etiology, pathophysiology, and novel treatment of DSD or adrenocortical disorders.

Pediatrics

Pediatrics, Neonatology, Pediatric Nephrology

Research in development of kidney function and morphogenesis, especially focusing on epigenetic modification in kidneys of preterm and low birth weight babies.

Gynecology

gynecologic oncology

The purpose of our basic research was to clarify the pathogenesis of precancerous lesions and treatment-resistant cancers and to develop new strategies for diagnosis and treatment. Furthermore, we performed the clinical research to establish the evidence on minimal invasive treatment, fertility-preserving treatment, and improvement of QOL in cancer survivors.

Obstetrics

Perinatal Medicine, Reproductive Medicine, Clinical Genetics, Embryology

Molecular biology concerning mammalian development; fetal medicine ranging from diagnostics to therapies; research and development of treatments of perinatal diseases utilizing mesenchyme stem cells.

Obstetrics

Reproductive Medicine, Clinical Genetics, Embryology, Regenerative Medicine

Oocytes maintain totipotency while undergoing meiosis and totipotency is unleashed at fertilization. Toward the elucidation of infertility mechanisms, we are conducting clinical research on artificial oocyte activation for restoring fertilization failure, and also basic research on the role of zygotic genome activation during embryogenesis and stem cell derivation.

Ophthalmology

Understanding Eyeball Optical System Conditions, Analyzing Visual Performance

Research related to visual optics and function. On the basis of the results of basic optical analysis using PC simulation, optical bench testing, and clinical data, we are trying to improve quality of vision, and aim to construct the ideal optical system for the human eye in daily activities.

Ophthalmology

Ophthalmology,Vitreoretinal disease

New surgical procedures for vitreoretinal surgery, clinical research for vitreoretinal diseases, and new drug treatments for Retinitis pigmentosa.

Ophthalmology

Vitreoretinal surgery, medical retina, high myopia, inherited retinal diseases

Investigating hypoxia responses of the retina, biological responses in light environments, visual restoration utilizing optogenetic technology and molecular and cellular mechanisms of myopia development and progression.

Dermatology

Autoimmunity, Allergies, Skin Barrier, Skin Immunity

Elucidating pathophysiological and immunological mechanisms in tissue-specific autoimmune disorders, and clarifying fundamental mechanisms of peripheral tolerance by analyzing the skin as an immune organ. Clarifying the mechanisms of allergy diseases at the molecular level from the point of view of skin barrier dysfunction, and developing novel therapeutic and preventive strategies. Elucidating the pathophysiological mechanisms of severe forms of drug eruption.

Dermatology

Skin immunology, autoimmune diseases, T cell biology

Elucidating pathophysiology of immune-related skin diseases, especially autoimmune blistering diseases and drug adverse reactions, via mainly understanding roles of T cells in the diseases and proposing new therapeutic approaches.

Dermatology

Dermatologic Oncology

Translational research to develop new treatments for skin cancers such as extramammary Paget's disease, malignant melanoma, and squamous cell carcinoma.

Urology

Understanding the Oncogenesis of Urological Cancers and Developing Novel Cancer Therapies

Aiming for an integrative understanding of the development of cancer from precancerous lesions and the mechanisms of metastasis; developing innovative new treatments with a focus on the cellular-biological features in cytokine production and neoangiogenesis, etc.

Urology

Pediatric urology and kidney transplantation

1)Analysis of mesenchymal stem cell therapy and its mechanism for renal fibrosis induced by obstructive uropathy; 2)Development of the noninvasive diagnostic method for vesicoureteral reflux, the most important underlying disease of urinary tract infection, using color Doppler ultrasonography